Anemia of inflammation: the hepcidin link
CN Roy, NC Andrews - Current opinion in hematology, 2005 - journals.lww.com
CN Roy, NC Andrews
Current opinion in hematology, 2005•journals.lww.comIncreasingly, experiments suggest the hepatocyte is not just the iron storage depot but is the
'command central'for the maintenance of iron homeostasis. It receives multiple signals
related to iron balance and responds via transcriptional control of hepcidin antimicrobial
peptide.
'command central'for the maintenance of iron homeostasis. It receives multiple signals
related to iron balance and responds via transcriptional control of hepcidin antimicrobial
peptide.
Summary
Increasingly, experiments suggest the hepatocyte is not just the iron storage depot but is the ‘command central’for the maintenance of iron homeostasis. It receives multiple signals related to iron balance and responds via transcriptional control of hepcidin antimicrobial peptide.
Lippincott Williams & Wilkins