[HTML][HTML] Purification and characterization of 1-O-acylceramide synthase, a novel phospholipase A2 with transacylase activity
A Abe, JA Shayman - Journal of Biological Chemistry, 1998 - ASBMB
A novel pathway for ceramide metabolism, 1-O-acylceramide formation, was previously
reported (Abe, A., Shayman, JA, and Radin, NS (1996) J. Biol. Chem. 271, 14383–14389). In
this pathway a fatty acid in the sn-2 position of phosphatidylethanolamine or
phosphatidylcholine is transferred to the 1-hydroxyl position of ceramide. An enzyme that
catalyzes the esterification of N-acetylsphingosine was purified from the postmitochondrial
supernatant of calf brain through consecutive steps, including ammonium sulfate …
reported (Abe, A., Shayman, JA, and Radin, NS (1996) J. Biol. Chem. 271, 14383–14389). In
this pathway a fatty acid in the sn-2 position of phosphatidylethanolamine or
phosphatidylcholine is transferred to the 1-hydroxyl position of ceramide. An enzyme that
catalyzes the esterification of N-acetylsphingosine was purified from the postmitochondrial
supernatant of calf brain through consecutive steps, including ammonium sulfate …
