Lipoprotein retention—and clues for atheroma regression
KJ Williams, I Tabas - Arteriosclerosis, Thrombosis, and Vascular …, 2005 - Am Heart Assoc
Arteriosclerosis, Thrombosis, and Vascular Biology, 2005•Am Heart Assoc
Subendothelial retention of apoB-lipoproteins is the key initiating event in atherosclerosis,
provoking a cascade of pathogenic responses. Dissection of the molecular participants
provides fresh insight into how this major killer might be reversed. Efflux of harmful lipids
derived from retained lipoproteins may be crucial in promoting beneficial remodeling of
lesions.
provoking a cascade of pathogenic responses. Dissection of the molecular participants
provides fresh insight into how this major killer might be reversed. Efflux of harmful lipids
derived from retained lipoproteins may be crucial in promoting beneficial remodeling of
lesions.
Subendothelial retention of apoB-lipoproteins is the key initiating event in atherosclerosis, provoking a cascade of pathogenic responses. Dissection of the molecular participants provides fresh insight into how this major killer might be reversed. Efflux of harmful lipids derived from retained lipoproteins may be crucial in promoting beneficial remodeling of lesions.
Am Heart Assoc