BackgroundPlasminogen‐deficient mice exhibit behavioral differences in response to stress,
including a markedly reduced acoustic startle reflex response compared with wild‐type (WT)
littermates. The acoustic startle reflex activates the hypothalamic–pituitary axis and is
modulated by these hormones. ObjectivesThe purpose of this study was to investigate
whether plasminogen plays a role in the processing of hormones in the hypothalamic–
pituitary axis. MethodsIn this study the concentration of plasma, pituitary, and brain …