Kinetics of changes in peritoneal cell populations following acute inflammation
MJ Melnicoff, PK Horan, PS Morahan - Cellular immunology, 1989 - Elsevier
The kinetics of macrophage (MΦ) recruitment to the peritoneum following the induction of
acute inflammation by thioglycollate broth (TG) was evaluated after prelabeling resident MΦ
with the fluorescent cell tracking dye, PKH-1. Most of the PKH-1-labeled resident MΦ
disappeared from the recoverable peritoneal cell population within the first hour after
injection of TG. This disappearance coincided with the inflammatory influx of neutrophils
(PMNs) and was sustained for at least 5 days after administration of TG, although the PMN …
acute inflammation by thioglycollate broth (TG) was evaluated after prelabeling resident MΦ
with the fluorescent cell tracking dye, PKH-1. Most of the PKH-1-labeled resident MΦ
disappeared from the recoverable peritoneal cell population within the first hour after
injection of TG. This disappearance coincided with the inflammatory influx of neutrophils
(PMNs) and was sustained for at least 5 days after administration of TG, although the PMN …
