SNARE complexes prepare for membrane fusion

JB Sørensen - Trends in neurosciences, 2005 - cell.com
Trends in neurosciences, 2005cell.com
According to a popular theory, the three presynaptic SNARE proteins (syntaxin 1,
synaptobrevin 2 and SNAP-25) drive neuroexocytosis by forming a complex that forces
vesicle and plasma membranes together. However, individual reactions in this process have
been difficult to resolve. Now, two groups have succeeded in studying a very early and a
very late step in the fusion process.
According to a popular theory, the three presynaptic SNARE proteins (syntaxin 1, synaptobrevin 2 and SNAP-25) drive neuroexocytosis by forming a complex that forces vesicle and plasma membranes together. However, individual reactions in this process have been difficult to resolve. Now, two groups have succeeded in studying a very early and a very late step in the fusion process.
cell.com