Plasma levels of factor XII, prekallikrein and high molecular weight kininogen in normal blood donors and patients having suffered venous thrombosis
MJ Gallimore, SL Harris, DW Jones, M Winter - Thrombosis research, 2004 - Elsevier
Introduction: The contact system proteins factor XII (FXII), prekallikrein (PK) and high
molecular weight kininogen (HK) have roles in coagulation, fibrinolysis, thrombin-induced
platelet activation, cell adhesion and angeogenisis. It has been suggested that inherited or
acquired deficiencies of these proteins may be risk factors for thrombosis. Studies on the
levels of FXII in plasma from normal and thrombotic patient populations have been reported,
to our knowledge however, no systematic study on plasma levels of PK and HK in large …
molecular weight kininogen (HK) have roles in coagulation, fibrinolysis, thrombin-induced
platelet activation, cell adhesion and angeogenisis. It has been suggested that inherited or
acquired deficiencies of these proteins may be risk factors for thrombosis. Studies on the
levels of FXII in plasma from normal and thrombotic patient populations have been reported,
to our knowledge however, no systematic study on plasma levels of PK and HK in large …
