In some patients with sodium sensitive type of hypertension or kidney disease, blood
pressure (BP) fails to dip during night and they have been called “non-dipper”, whereas
those with a normal nocturnal dip are called “dipper”. Many investigators reported that non-
dippers were certainly exposed to greater risks of cardiovascular complications. We have
recently proposed that kidneys play an important role in determining the circadian rhythm of
BP, in addition to long-term BP regulation. When sodium intake is high, the defect in sodium …