Cloning and characterization of a novel human leptin receptor overlapping transcript-like 1 gene (LEPROTL1)
Y Huang, K Ying, Y Xie, Z Zhou, W Wang… - … et Biophysica Acta (BBA …, 2001 - Elsevier
A new full-length cDNA encoding a novel protein was isolated from our human fetal brain
cDNA library. The cDNA consists of 2701 bp and has a putative open reading frame
encoding 131 amino acids which possesses a JAK binding site (Pro46–Ile–Pro48 which is
preceded by a cluster of hydrophobic residues) and is highly homologous to the leptin
receptor gene-related protein (OB-RGRP). Northern blot analysis showed that this new gene
is widely expressed in human tissues and radiation hybrid mapping placed the gene to …
cDNA library. The cDNA consists of 2701 bp and has a putative open reading frame
encoding 131 amino acids which possesses a JAK binding site (Pro46–Ile–Pro48 which is
preceded by a cluster of hydrophobic residues) and is highly homologous to the leptin
receptor gene-related protein (OB-RGRP). Northern blot analysis showed that this new gene
is widely expressed in human tissues and radiation hybrid mapping placed the gene to …