Adipose tissue contains many cell types. Among the more abundant are adipocytes,
preadipocytes, immune cells, and endothelial cells. During times of excess caloric intake,
these cells have to adjust and remodel to accommodate the increased demand for
triglyceride storage. Based on a comprehensive analysis of the total adipose tissue
secretome, this article focuses on three areas of adipokine biology:(1) What changes the
extracellular matrix of adipose tissue during the development of obesity?(2) Does the …