Cardiovascular effects of the nitric oxide synthase inhibitor NG-methyl-L-arginine hydrochloride (546C88) in patients with septic shock: results of a randomized, double …
Objective To assess the hemodynamic effects of the nitric oxide synthase inhibitor 546C88
in patients with septic shock, although this was not a stated aim of the protocol. The
predefined primary efficacy objective of the protocol was resolution of shock determined at
the end of a 72-hr treatment period. Design
in patients with septic shock, although this was not a stated aim of the protocol. The
predefined primary efficacy objective of the protocol was resolution of shock determined at
the end of a 72-hr treatment period. Design
