Dengue haemorrhagic fever: a pathological study
T Burke - Transactions of the Royal Society of Tropical Medicine …, 1968 - Elsevier
The necropsy findings in 12 cases of dengue haemorrhagic fever are described. Interstitial
pneumonitis was present in all 12, and protein-rich serous effusions were found in 9. In most
patients deposits of fibrin could be demonstrated within blood vessel walls in the spleen,
and less frequently in pancreas and lung. Although the pathogenesis of this fibrin deposition
is unknown, it is believed to be a manifestation of increased vascular permeability.
Paracentral areas of zonal necrosis were found in the liver in 4 cases; Councilman-like …
pneumonitis was present in all 12, and protein-rich serous effusions were found in 9. In most
patients deposits of fibrin could be demonstrated within blood vessel walls in the spleen,
and less frequently in pancreas and lung. Although the pathogenesis of this fibrin deposition
is unknown, it is believed to be a manifestation of increased vascular permeability.
Paracentral areas of zonal necrosis were found in the liver in 4 cases; Councilman-like …
