An adherent Gardnerella vaginalis biofilm persists on the vaginal epithelium after standard therapy with oral metronidazole
A Swidsinski, W Mendling, V Loening-Baucke… - American journal of …, 2008 - Elsevier
OBJECTIVE: The purpose of this study was to determine the efficacy of standard treatment
with oral metronidazole in the eradication of the bacterial vaginosis biofilm. STUDY DESIGN:
We conducted an interventional follow-up study in which 18 patients with bacterial vaginosis
were treated with oral metronidazole during 1 week and subsequently had a single random
follow-up assessment at 1-week intervals, up to 5 weeks, with 3 patients representing each
point in time. Follow-up assessment included conventional scoring of the vaginal microflora …
with oral metronidazole in the eradication of the bacterial vaginosis biofilm. STUDY DESIGN:
We conducted an interventional follow-up study in which 18 patients with bacterial vaginosis
were treated with oral metronidazole during 1 week and subsequently had a single random
follow-up assessment at 1-week intervals, up to 5 weeks, with 3 patients representing each
point in time. Follow-up assessment included conventional scoring of the vaginal microflora …