Comparison of single-dose vs one-week course of metronidazole for symptomatic bacterial vaginosis
J Swedberg, JF Steiner, F Deiss, S Steiner… - Jama, 1985 - jamanetwork.com
In a prospective, single-blind, randomized study, a single 2-g dose of metronidazole was
compared with a seven-day course of 500 mg given twice daily in the treatment of
symptomatic vaginal discharge associated withGardnerella vaginalis. Based on resolution of
symptoms and on cultures negative forG vaginalis, 86%(40/46) of women treated with the
single dose and 97%(35/36) of women treated with the seven-day course were considered
cured at seven to ten days after treatment. Evaluation at 21 days after treatment, however …
compared with a seven-day course of 500 mg given twice daily in the treatment of
symptomatic vaginal discharge associated withGardnerella vaginalis. Based on resolution of
symptoms and on cultures negative forG vaginalis, 86%(40/46) of women treated with the
single dose and 97%(35/36) of women treated with the seven-day course were considered
cured at seven to ten days after treatment. Evaluation at 21 days after treatment, however …