Free radical mechanisms in tissue injury
TF Slater - Cell function and disease, 1988 - Springer
TF Slater
Cell function and disease, 1988•SpringerFree radicals are molecules or molecular fragments containing a single unpaired electron. In
general, free radicals are reactive chemically, some (eg HO•) being extremely reactive.
However, certain types of free radical, such as nitroxyl-radicals and free radicals stabilized
by steric or derealization features, are much less reactive and a few (eg diphenyl picryl
hydrazyl) are stable enough to be crystallised and stored at temperatures above 0°. Table 1
gives the general structures of free radicals that will be discussed in this short review.
general, free radicals are reactive chemically, some (eg HO•) being extremely reactive.
However, certain types of free radical, such as nitroxyl-radicals and free radicals stabilized
by steric or derealization features, are much less reactive and a few (eg diphenyl picryl
hydrazyl) are stable enough to be crystallised and stored at temperatures above 0°. Table 1
gives the general structures of free radicals that will be discussed in this short review.
Abstract
Free radicals are molecules or molecular fragments containing a single unpaired electron. In general, free radicals are reactive chemically, some (e.g. HO•) being extremely reactive. However, certain types of free radical, such as nitroxyl-radicals and free radicals stabilized by steric or derealization features, are much less reactive and a few (e.g. diphenyl picryl hydrazyl) are stable enough to be crystallised and stored at temperatures above 0°. Table 1 gives the general structures of free radicals that will be discussed in this short review.
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