Free radical mechanisms in tissue injury

TF Slater - Cell function and disease, 1988 - Springer
TF Slater
Cell function and disease, 1988Springer
Free radicals are molecules or molecular fragments containing a single unpaired electron. In
general, free radicals are reactive chemically, some (eg HO•) being extremely reactive.
However, certain types of free radical, such as nitroxyl-radicals and free radicals stabilized
by steric or derealization features, are much less reactive and a few (eg diphenyl picryl
hydrazyl) are stable enough to be crystallised and stored at temperatures above 0°. Table 1
gives the general structures of free radicals that will be discussed in this short review.
Abstract
Free radicals are molecules or molecular fragments containing a single unpaired electron. In general, free radicals are reactive chemically, some (e.g. HO•) being extremely reactive. However, certain types of free radical, such as nitroxyl-radicals and free radicals stabilized by steric or derealization features, are much less reactive and a few (e.g. diphenyl picryl hydrazyl) are stable enough to be crystallised and stored at temperatures above 0°. Table 1 gives the general structures of free radicals that will be discussed in this short review.
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