[HTML][HTML] Transfer of maternal cholesterol to embryo and fetus in pregnant mice
S Yoshida, Y Wada - Journal of lipid research, 2005 - ASBMB
Cholesterol is essential for antenatal development. However, the transport of maternal
cholesterol to the embryo has not been sufficiently studied, and that to the fetus is still
controversial. To this end, a 1 mg dose of [3, 4-13 C 2] cholesterol was injected daily into
pregnant mice and the labeled cholesterol was measured by gas chromatography-mass
spectrometry. After venous injections from days 10 to 17 of gestation,[13 C] cholesterol
levels in total (12 C and 13 C) cholesterol were increased to 5.1% and 2.8% in maternal and …
cholesterol to the embryo has not been sufficiently studied, and that to the fetus is still
controversial. To this end, a 1 mg dose of [3, 4-13 C 2] cholesterol was injected daily into
pregnant mice and the labeled cholesterol was measured by gas chromatography-mass
spectrometry. After venous injections from days 10 to 17 of gestation,[13 C] cholesterol
levels in total (12 C and 13 C) cholesterol were increased to 5.1% and 2.8% in maternal and …
