Synaptotagmin II. A novel differentially distributed form of synaptotagmin
M Geppert, BT Archer, TC Südhof - Journal of Biological Chemistry, 1991 - ASBMB
Synaptotagmin is a synaptic vesicle membrane protein with properties suggestive of a role
in synaptic vesicle exocytosis (Perin, MS, Fried, VA, Mignery, GA, Jahn, R., and Südhof, TC
(1990) Nature 345, 260-263). Here, we report the structure of a novel form of synaptotagmin
named synaptotagmin II that is highly homologous to the originally described
synaptotagmin, now referred to as synaptotagmin I. Synaptotagmins I and II exhibit the same
overall structure, containing a small intravesicular sequence that is glycosylated, a single …
in synaptic vesicle exocytosis (Perin, MS, Fried, VA, Mignery, GA, Jahn, R., and Südhof, TC
(1990) Nature 345, 260-263). Here, we report the structure of a novel form of synaptotagmin
named synaptotagmin II that is highly homologous to the originally described
synaptotagmin, now referred to as synaptotagmin I. Synaptotagmins I and II exhibit the same
overall structure, containing a small intravesicular sequence that is glycosylated, a single …
