Subclinical vitamin D deficiency
L Cianferotti, C Marcocci - Best Practice & Research Clinical Endocrinology …, 2012 - Elsevier
The optimal vitamin D status, as defined by serum 25-hydroxyvitamin D [25 (OH) D], is still
controversial. Some individuals are at risk for subclinical vitamin D deficiency, as defined by
serum 25 (OH) D levels between 25 and 75 nmol/L, and up to 80–100% of the entire
population can display inadequate serum 25 (OH) D values depending on latitude and
seasonality. The clinical manifestation of extreme vitamin D deficiency, ie rickets and
osteomalacia, are rare. Levels of 25 (OH) D≥ 50 nmol/L are required for optimal …
controversial. Some individuals are at risk for subclinical vitamin D deficiency, as defined by
serum 25 (OH) D levels between 25 and 75 nmol/L, and up to 80–100% of the entire
population can display inadequate serum 25 (OH) D values depending on latitude and
seasonality. The clinical manifestation of extreme vitamin D deficiency, ie rickets and
osteomalacia, are rare. Levels of 25 (OH) D≥ 50 nmol/L are required for optimal …
