Characterization of a mannose and N-acetylglucosamine-specific lectin present in rat hepatocytes.

Y Maynard, JU Baenziger - Journal of Biological Chemistry, 1982 - ASBMB
We have isolated and characterized a Man/GlcNAc-specific lectin from rat liver. The
specificity of this lectin resembles that of the previously reported Man/GlcNAc-specific
receptor activity present on the surface of hepatic reticuloendothelial cells when tested with
simple sugars, but can be distinguished from the latter by utilizing characterized
glycopeptides and glycoproteins. The lectin isolated from liver originates predominantly from
hepatocytes rather than reticuloendothelial cells. It is found in microsomes upon subcellular …