Neuropeptide Y: A stressful review

F Reichmann, P Holzer - Neuropeptides, 2016 - Elsevier
Stress is defined as an adverse condition that disturbs the homeostasis of the body and
activates adaptation responses. Among the many pathways and mediators involved,
neuropeptide Y (NPY) stands out due to its unique stress-relieving, anxiolytic and
neuroprotective properties. Stress exposure alters the biosynthesis of NPY in distinct brain
regions, the magnitude and direction of this effect varying with the duration and type of
stress. NPY is expressed in particular neurons of the brainstem, hypothalamus and limbic …