Small cell lung cancer

GP Kalemkerian, W Akerley, P Bogner… - Journal of the National …, 2013 - jnccn.org
GP Kalemkerian, W Akerley, P Bogner, H Borghaei, LQM Chow, RJ Downey, L Gandhi
Journal of the National Comprehensive Cancer Network, 2013jnccn.org
Neuroendocrine tumors account for approximately 20% of lung cancers; most (≈ 15%) are
small cell lung cancer (SCLC). These NCCN Clinical Practice Guidelines in Oncology for
SCLC focus on extensive-stage SCLC because it occurs more frequently than limited-stage
disease. SCLC is highly sensitive to initial therapy; however, most patients eventually die of
recurrent disease. In patients with extensive-stage disease, chemotherapy alone can
palliate symptoms and prolong survival in most patients; however, long-term survival is rare …
Neuroendocrine tumors account for approximately 20% of lung cancers; most (≈15%) are small cell lung cancer (SCLC). These NCCN Clinical Practice Guidelines in Oncology for SCLC focus on extensive-stage SCLC because it occurs more frequently than limited-stage disease. SCLC is highly sensitive to initial therapy; however, most patients eventually die of recurrent disease. In patients with extensive-stage disease, chemotherapy alone can palliate symptoms and prolong survival in most patients; however, long-term survival is rare. Most cases of SCLC are attributable to cigarette smoking; therefore, smoking cessation should be strongly promoted.
jnccn.org