Increased surface expression of NOTCH on memory T cells in peripheral blood from patients with asthma

I Tindemans, H Vroman, M Lukkes… - Journal of Allergy and …, 2019 - jacionline.org
We used multicolor flow cytometry to quantify expression of NOTCH1 and NOTCH2 on T
cells present in peripheral blood samples from 59 patients with asthma (inclusion and
exclusion criteria are detailed in Table E1 in this article's Online Repository at www.
jacionline. org) and from 28 age/sex-matched healthy controls (HCs). The study was
approved by the Medical Ethical Committee of the Erasmus MC Rotterdam; written informed
consent was obtained from every participant before study inclusion. Patients were …