Peanut allergy is typically lifelong, often severe, and potentially fatal. Because reactions can
occur from small amounts, the allergy presents patients with significant obstacles to avoid
allergic reactions. In North America and the United Kingdom, prevalence rates among
schoolchildren are now in excess of 1%, framing an increasing public health concern and
raising research questions about environmental, immunologic, and genetic factors that may
influence outcomes of peanut allergy. This review focuses on recent observations that …