CCR4+ memory CD4+ T lymphocytes are increased in peripheral blood and lesional skin from patients with atopic dermatitis
T Nakatani, Y Kaburagi, Y Shimada, M Inaoki… - Journal of allergy and …, 2001 - Elsevier
Background: Recent studies have reported that TH1 and TH2 cells express CXCR3 and
CCR4, respectively. Objective: Our goal was to assess the association of CCR4 and CXCR3
expression with TH2 and TH1 cells and association of CCR4 and CXCR3 expression with
inflammation in patients with atopic dermatitis (AD). Methods: Intracellular cytokine
production and chemokine receptor expression in blood T cells were examined by flow
cytometry. Immunohistochemical expression of chemokine receptors was also investigated …
CCR4, respectively. Objective: Our goal was to assess the association of CCR4 and CXCR3
expression with TH2 and TH1 cells and association of CCR4 and CXCR3 expression with
inflammation in patients with atopic dermatitis (AD). Methods: Intracellular cytokine
production and chemokine receptor expression in blood T cells were examined by flow
cytometry. Immunohistochemical expression of chemokine receptors was also investigated …
