Variability in viral pathogenesis: modeling the dynamic of acute and persistent infections
PV Lidsky, R Andino, IM Rouzine - Current opinion in virology, 2017 - Elsevier
Highlights•Variability in outcomes of virus infections is a major concern for public
health.•Current epidemiological models are not able to explain these variations.•We
propose that variability in the infection outcome could be a part of virus reproduction
strategy.Virus infection often results in diverse outcomes. This variability of virus
pathogenesis is not well understood. Here we revise theoretical arguments to further our
understanding of factors controlling infection and its severity. We propose that variability in …
health.•Current epidemiological models are not able to explain these variations.•We
propose that variability in the infection outcome could be a part of virus reproduction
strategy.Virus infection often results in diverse outcomes. This variability of virus
pathogenesis is not well understood. Here we revise theoretical arguments to further our
understanding of factors controlling infection and its severity. We propose that variability in …
