National disease burden of respiratory viruses detected in children by polymerase chain reaction

KJ Henrickson, S Hoover, KS Kehl… - The Pediatric infectious …, 2004 - journals.lww.com
KJ Henrickson, S Hoover, KS Kehl, W Hua
The Pediatric infectious disease journal, 2004journals.lww.com
Background. The epidemiology of community-acquired respiratory viruses at the Children's
Hospital of Wisconsin between 1996 and 1998 was examined with molecular [multiplex (M)
PCR] and standard virologic methods. Methods and results. A total of 3325 patients with
lower respiratory infection (LRI)[bronchiolitis (42%), pneumonia (38%) and croup (12%)]
were identified. It is estimated that 545 000 LRI hospitalizations occur each year in the
United States in children younger than 18 years old (viral, 428 000; pneumonia, 221 000; …
Abstract
Background.
The epidemiology of community-acquired respiratory viruses at the Children’s Hospital of Wisconsin between 1996 and 1998 was examined with molecular [multiplex (M) PCR] and standard virologic methods.
Methods and results.
A total of 3325 patients with lower respiratory infection (LRI)[bronchiolitis (42%), pneumonia (38%) and croup (12%)] were identified. It is estimated that 545 000 LRI hospitalizations occur each year in the United States in children younger than 18 years old (viral, 428 000; pneumonia, 221 000; bronchiolitis, 222 000; croup, 65 000), including a continued increase in bronchiolitis hospitalizations (47.8/1000;< 1 year).
Lippincott Williams & Wilkins