[HTML][HTML] Belatacept-based immunosuppression with simultaneous calcineurin inhibitor avoidance and early corticosteroid withdrawal: a prospective, randomized …
ES Woodle, DB Kaufman, AR Shields, J Leone… - American Journal of …, 2020 - Elsevier
Simultaneous calcineurin inhibitor avoidance (CNIA) and early corticosteroid withdrawal
(ESW) have not been achieved primarily due to excessive acute rejection. This trial
compared 2 belatacept-based CNIA/ESW regimens with a tacrolimus-based ESW regimen.
Kidney transplant recipients were randomized to receive alemtuzumab/belatacept, rabbit
anti-thymocyte globulin (rATG)/belatacept, or rATG/tacrolimus. The combinatorial primary
endpoint consisted of patient death, renal allograft loss, or a Modification of Diet in Renal …
(ESW) have not been achieved primarily due to excessive acute rejection. This trial
compared 2 belatacept-based CNIA/ESW regimens with a tacrolimus-based ESW regimen.
Kidney transplant recipients were randomized to receive alemtuzumab/belatacept, rabbit
anti-thymocyte globulin (rATG)/belatacept, or rATG/tacrolimus. The combinatorial primary
endpoint consisted of patient death, renal allograft loss, or a Modification of Diet in Renal …
