Progress and challenges in analyzing rodent energy expenditure
R Fernández-Verdejo, E Ravussin, JR Speakman… - Nature …, 2019 - nature.com
Nature methods, 2019•nature.com
Whole-body energy expenditure is the summed metabolic activities of tissues and, to
remove the influence of body size, ratios of energy expenditure to body mass are often
applied but can generate spurious differences. In 2011, a group of experts proposed
adoption of ANCOVA for the analysis of metabolic rate but, seven years later, analyses
based on ratios remain the most frequent. We discuss some of the barriers to adopting better
analytical procedures.
remove the influence of body size, ratios of energy expenditure to body mass are often
applied but can generate spurious differences. In 2011, a group of experts proposed
adoption of ANCOVA for the analysis of metabolic rate but, seven years later, analyses
based on ratios remain the most frequent. We discuss some of the barriers to adopting better
analytical procedures.
Whole-body energy expenditure is the summed metabolic activities of tissues and, to remove the influence of body size, ratios of energy expenditure to body mass are often applied but can generate spurious differences. In 2011, a group of experts proposed adoption of ANCOVA for the analysis of metabolic rate but, seven years later, analyses based on ratios remain the most frequent. We discuss some of the barriers to adopting better analytical procedures.
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