Free fatty acid metabolic profile and biomarkers of isolated post-challenge diabetes and type 2 diabetes mellitus based on GC–MS and multivariate statistical analysis

L Liu, Y Li, C Guan, K Li, C Wang, R Feng… - … of Chromatography B, 2010 - Elsevier
Isolated post-challenge diabetes (IPD, 2h-PG≥ 11.1 mmol/L and FPG< 7.0 mmol/L) is often
ignored in screening for diabetes by fasting plasma glucose (FPG) levels. The aim of this
study was to investigate the metabolic profiles of serum free fatty acids (FFAs) and to identify
biomarkers that can be used to distinguish patients with IPD from those with type 2 diabetes
mellitus (T2DM) or healthy control individuals. FFA profiles of the subjects were investigated
using gas chromatography–mass spectrometry (GC–MS). Principal component analysis …