Does endothelium buffer fat?
1220 Circulation Research April 14, 2017 however, it is important to note that ECs likely
derive most ATP from glycolysis, with little contribution from fats, and that ECs have constant
access to plasma nutrients. Thus, it seems unlikely that ECs significantly rely on LDs to store
fats for later use to generate ATP. Third, storage of fats in LDs potentially provides a
significant systemic buffer against fat overload. There are an estimated 1 to 3 trillion ECs in
the human body, permeating nearly every organ, with an estimated total volume on the order …
derive most ATP from glycolysis, with little contribution from fats, and that ECs have constant
access to plasma nutrients. Thus, it seems unlikely that ECs significantly rely on LDs to store
fats for later use to generate ATP. Third, storage of fats in LDs potentially provides a
significant systemic buffer against fat overload. There are an estimated 1 to 3 trillion ECs in
the human body, permeating nearly every organ, with an estimated total volume on the order …
1220 Circulation Research April 14, 2017 however, it is important to note that ECs likely derive most ATP from glycolysis, with little contribution from fats, and that ECs have constant access to plasma nutrients. Thus, it seems unlikely that ECs significantly rely on LDs to store fats for later use to generate ATP.
Third, storage of fats in LDs potentially provides a significant systemic buffer against fat overload. There are an estimated 1 to 3 trillion ECs in the human body, permeating nearly every organ, with an estimated total volume on the order of 1 L. 7, 8 The interface between ECs and plasma is between 4000 and 7000 m2, equivalent to the surface of> 20 tennis courts.
Am Heart Assoc
