Hyperlipoproteinemia
JW Gofman, L Rubin, JP McGinley… - The American journal of …, 1954 - amjmed.com
JW Gofman, L Rubin, JP McGinley, HB Jones
The American journal of medicine, 1954•amjmed.com1. The serum lipoproteins of cases of xanthoma tendinosum, xanthoma tuberosum,
xanthelasma, the nephrotic syndrome, biliary cirrhosis, myxedema and" essential"
hyperlipemia are compared with each other and with the normal serum lipoprotein
distribution. 2.2. The diagnosis of the nephrotic syndrome can almost always be made by the
serum lipoprotein spectrum alone. 3.3. The diagnosis of biliary cirrhosis can almost always
be made by the serum lipoprotein spectrum alone. 4.4. Xanthoma tuberosum and" essential" …
xanthelasma, the nephrotic syndrome, biliary cirrhosis, myxedema and" essential"
hyperlipemia are compared with each other and with the normal serum lipoprotein
distribution. 2.2. The diagnosis of the nephrotic syndrome can almost always be made by the
serum lipoprotein spectrum alone. 3.3. The diagnosis of biliary cirrhosis can almost always
be made by the serum lipoprotein spectrum alone. 4.4. Xanthoma tuberosum and" essential" …
Abstract
- 1.1. The serum lipoproteins of cases of xanthoma tendinosum, xanthoma tuberosum, xanthelasma, the nephrotic syndrome, biliary cirrhosis, myxedema and "essential" hyperlipemia are compared with each other and with the normal serum lipoprotein distribution.
- 2.2. The diagnosis of the nephrotic syndrome can almost always be made by the serum lipoprotein spectrum alone.
- 3.3. The diagnosis of biliary cirrhosis can almost always be made by the serum lipoprotein spectrum alone.
- 4.4. Xanthoma tuberosum and "essential" hyperlipemia can almost always be differentiated from the other conditions by means of the serum lipoproteins alone and usually patients with these conditions can be differentiated from each other by this test.
- 5.5. Xanthoma tendinosum, xanthelasma and myxedema can be distinguished from the other conditions described here but the serum lipoprotein spectra in these cases are sufficiently similar to each other to make it difficult or impossible to make the differential diagnosis among them by the serum lipoproteins alone.
- 6.6. It is suggested that the serum lipoprotein spectrum be considered the standard diagnostic feature of these illnesses rather than such nebulous criteria as turbidity of sera, or such non-distinguishing criteria as serum cholesterol determinations.
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